Locomotion Is Increased in A11-Lesioned Mice With Iron Deprivation
نویسندگان
چکیده
منابع مشابه
Locomotion is increased in a11-lesioned mice with iron deprivation: a possible animal model for restless legs syndrome.
Restless legs syndrome (RLS) is a common neurologic condition involving iron and dopamine systems. We sought to create an animal model consistent with RLS based on current understanding of human pathology. We performed bilateral 6-hydroxydopamine (6-OHDA) lesioning in the A11 nucleus of C57BL/6 mice and deprived a subset of mice from dietary iron to observe whether these manipulations can incre...
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ژورنال
عنوان ژورنال: Journal of Neuropathology and Experimental Neurology
سال: 2007
ISSN: 0022-3069
DOI: 10.1097/nen.0b013e3180517b5f